LIPORASE

LIPORASE

LIPORASE is a highly effective enzymatic solution containing Hyaluronidase, specifically formulated to dissolve hyaluronic acid (HA) fillers. Manufactured in Korea, this product is widely used in aesthetic medicine to correct undesired outcomes from HA-based procedures, such as overfilling, uneven distribution, incorrect placement, or vascular complications. LIPORASE ensures safe, targeted correction and is also employed in emergency medical situations related to filler misuse.

Key Features and Benefits of LIPORASE 

• Fast-acting enzyme that breaks down hyaluronic acid through hydrolysis

• Ideal for correcting excess or misplaced dermal filler injections

• Can reverse unsatisfactory filler results within 24–48 hours

• High effectiveness with a dissolution rate of up to 90%

• Also used in fat-melting procedures as a supplement treatment

• Suitable for intramuscular or subcutaneous injection

• Frequently used in conjunction with topical anesthetics for added patient comfort

Product Composition and Packaging

• Active Ingredient: Hyaluronidase (Freeze-dried powder)

• Form: White lyophilized powder

• Units per Vial: 1500 Units

• Pack Size: 10 vials per box

• Dilution Recommendation: Typically mixed with 3 ml of normal saline prior to injection

Primary Uses

• Correction of misplaced or excessive hyaluronic acid filler

• Reversal of HA-based cosmetic treatments in case of dissatisfaction

• Emergency treatment in cases of intravascular injection of HA fillers

• Management of complications like granulomas and skin necrosis

• Supplemental use in non-invasive fat layer reduction procedures

Application Areas

• Facial regions treated with HA-based dermal fillers

• Areas affected by filler-related vascular occlusion

• Fat-reduction zones in body sculpting procedures

Effectiveness and Onset

• Hydrolysis begins almost immediately after injection

• Full effect is typically visible within 24 hours

• Due to individual body responses, full absorption may take longer in some cases

Storage Conditions of LIPORASE

• Unopened vials should be stored at 2° to 8°C in a refrigerator

• Do not freeze

• Protect from sunlight

• Once diluted, the solution can be stored below 30°C for up to 2 weeks

• Do not use if the solution becomes discolored or precipitates form

Possible Side Effects

Common reactions include:

• Pain at the injection site

• Mild redness, itching, or swelling

Serious but rare side effects include:

• Allergic reactions (e.g., facial swelling, throat tightness)

• Difficulty breathing

• Blurred vision

• Irregular heartbeat

• Fever

Patients experiencing severe reactions should seek immediate medical attention.

Contraindications

• Not to be used to enhance absorption of dopamine or similar drugs

• Not indicated for reducing edema from bites or stings

• Avoid use in individuals with known hypersensitivity to hyaluronidase

• Consult a physician before use during pregnancy or breastfeeding due to lack of safety data

Shipping and Availability

• Origin: Korea

• Availability: Ships globally (international shipping available)

Conclusion
LIPORASE is a reliable and essential tool for aesthetic professionals, ensuring safe correction of HA filler complications and providing emergency support when required. Its proven efficacy, versatility, and safety make it a must-have in advanced cosmetic and clinical practices.